The role of biomarkers and molecular profiling in cancer diagnosis and treatment continues to expand. In oncology, a biomarker can indicate cancer type, how a cancer will progress if left untreated, what specific treatment may be most effective for a given cancer, and how well treatment is working over time. For five of the most common types of cancer (lung, prostate, colorectal, breast, and skin), there are more than 75 biomarkers used in clinical practice. The sheer number of treatment options across tumor types and the complexity of delivering care makes it difficult for cancer care providers to integrate new therapeutics, like biomarker testing, into their practices.
Barriers to using biomarker testing are common. Respondents to ACCC’s 2018 Trending Now in Cancer Care Survey indicate that insurance coverage, reimbursement, and insufficient protocols are among the issues working against the widespread implementation of biomarker testing in oncology practices.
To help cancer care providers surmount these and other barriers and enhance their knowledge of this rapidly evolving treatment area, ACCC launched the first phase of BiomarkerLIVE in April 2019. Since then, ACCC has worked with clinical experts and industry leaders to develop a common lexicon of biomarker terminology to promote better communication among cancer care teams; establish a resource library of materials relevant to cancer biomarkers and biomarker testing; and host a how-to webinar that explores how cancer programs can use these tools to implement effective biomarker testing protocols for their patients.
Building on the success of BiomarkerLIVE’s launch, Phase 2 will help cancer providers better understand what is needed to facilitate the integration of precision medicine into everyday practice. The objective of this phase is twofold:
This webinar will review how the steps in the life cycle of a patient specimen can affect its molecular integrity and molecular analysis results. Our expert speaker will define the roles of stewardship across the specimen chain of custody, discuss common factors that compromise specimen fitness for molecular testing, and describe solutions to improve preanalytics and tissue stewardship.
Two thought leaders who have deep knowledge of—and experience in—biomarker testing in patients with hematologic malignancies will discuss best practices for biomarker testing in chronic lymphocytic leukemia (CLL) and multiple myeloma based on patient case discussions and the latest guidelines.
Take a deeper dive into the differences between germline and somatic mutations and what this means for patients with cancer and their families. Considerations for tumor types where somatic and germline testing comes into play for colorectal, ovarian, pancreatic, and prostate cancers will be discussed.
Presented at the 2020 ASCO Virtual Scientific Program
Talking with Your Patients About Biomarker Testing in Cancer Care - Provider Tips
This fact sheet supplies information to assist providers in talking with patients about biomarker testing and its role in their care.
Conversation Guide: Biomarker Testing and its Role in Your Cancer Journey
A set of questions to guide patient-provider conversations related to biomarker testing. Type answers in this fillable PDF, or print blank copies for patients to write their own notes.
Biomarker Testing in Practice: Process Improvement Toolkit
Review the four key elements needed when developing a precision medicine program that successfully incorporates biomarker testing.
Application of Biomarkers in Clinical Trials
This white paper details considerations when determining to conduct biomarker testing on a patient, and the role the test results may play in potentially making that patient eligible for future clinical trials.
Biomarker testing is crucial to precision medicine, but barriers still exist. Learn from two healthcare advocates about recent policy changes designed to ensure better access to biomarker testing.
Learn about the current clinical applications of liquid biopsies, associated reimbursement issues, and what you can do to implement these tests at your program.
BiomarkerLIVE Project from the Association of Community Cancer Centers Supports Providers in Integration of Precision Medicine into Everyday Practice
April 29, 2020