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Research & Clinical Trials

Clinical trials can be a lifeline for patients with cancer, providing leading-edge care by clinicians dedicated to a specific disease, and the oncology community is filled with stories of patients whose lives were improved and/or extended due to participation in a trial. Despite the potential of clinical research to improve outcomes for patients with cancer, enrollment in trials remains stubbornly low—fewer than 3% of cancer patients in the U.S. participate.1According to a review of 7,776 adult oncology trials between 2005 and 2011, 20% closed early due to failure to meet their enrollment targets.2

Featured Program

ACCC Community Oncology Research Institute

The Association of Community Cancer Centers (ACCC) has established the ACCC Community Oncology Research Institute (ACORI) to build on its existing mission to close the gap in cancer research through optimal oncology partnerships.
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ACORI Call to Action Executive Summary

ACORI Executive SummaryThe ACORI Call to Action Summit: Activating Equity in Community Oncology Research—in collaboration with Stand Up to Cancer—identified concrete strategies for engaging patients, caregivers, and their communities to strengthen oncology research. More than 120 people from 60 organizations generated 200+ ideas for action items to make cancer care research more diverse, equitable, and accessible.

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Cancer Buzz Podcasts

  • Cannabis and Cancer: Developing a Patient Clinic — [PODCAST] Ep 86
    Jul 12, 2022
    The demand for medical cannabis education from both providers and patients is increasing dramatically as stigma on its use decreases. Learn how the Cannabis and Cancer Research and Education Clinic (CanCaRE) is helping meet this growing need. 
  • [PODCAST] Ep 84: Increasing Clinical Trial Access for Blood Cancers
    Jun 7, 2022

    Clinical trials are the best instrument to advance treatment for blood cancers, but numerous challenges exist around trial identification, enrollment, and participation. We’ll hear perspectives from a community provider and patient advocacy organization on immediate—and forward-thinking—solutions to help this population better access clinical trials, including a tool from the Leukemia and Lymphoma Society to help patients identify cancer clinical trials that may be a fit.

  • [MINI-PODCAST] Ep 65: Integrating Advanced Practitioners into Research
    Aug 3, 2021
    In this episode, we'll hear the evolution of the advanced practitioners (APs) role at her institution, where APs have a larger voice in the research process and clinical trial protocols, serve as champions to advocate for patients and research staff, and collaborate with their team to promote best practices in clinical trial delivery.
  • [MINI-PODCAST] Ep 63: Advanced Practitioners’ Role in Research
    Jul 13, 2021

    In this episode, we'll explore how oncology advanced practitioners (APs) can play a greater role in clinical research and, according to a recent national study, have a strong interest in doing so.

  • [MINI-PODCAST] Ep 60: Advancing Clinical Trial Equity
    Jun 15, 2021

    In this episode, Colleen Lewis, MSN, ANP-BC, AOCNP, talks about the critical role oncology advanced practitioners can play in moving the needle on equity and inclusion in cancer clinical trials.

  • [PODCAST] Ep 44: The Promise of Bispecific Antibodies
    Nov 24, 2020

    Learn about the latest promising breakthroughs in immunotherapy, the challenges facing their widespread use, and what your cancer team needs to know about the future of cancer treatment.

  • [MINI-PODCAST] Ep 38: Improving Community Clinical Trial Participation
    Oct 13, 2020

    Learn about the importance of reaching diverse populations with clinical trials where they live and how one clinical trial has prioritized community engagement.

  • [PODCAST] Ep 26: IO Clinical Trials During COVID-19
    Jun 23, 2020

    We explore how immunotherapy clinical trials have been affected by the pandemic and what cancer programs can do to safely and effectively administer clinical trials.

  • [PODCAST] Ep 12: What's Trending in Cancer Care
    Feb 26, 2020

    Discover the results of the 2019 Trending Now in Cancer Care Survey—what tops the list of challenges, what areas are trending towards growth, and how cancer programs are evolving to meet the demands of 21st-century cancer care delivery.

  • [PODCAST] Ep 06: Clinical Trial Access in Rural Areas
    Oct 16, 2019

    Learn how a rural health system harnessed its passion and creativity to work around obstacles to clinical trial access and ensure its patients have access to cutting-edge cancer treatments. 

Training Program

  • An online implicit bias training program that presents the broader context of structural and systemic racism, the role of implicit bias in clinical trial selection, vignettes with real-world examples of implicit bias, and guidance for mitigating disparities in cancer research settings.

Facilitation Guide

To facilitate fruitful discussions with staff around implicit bias, this Just Ask™ Training Facilitation Guide has been developed to identify feasible action steps to support implementation of a Just Ask™ strategy in your research site or cancer program or practice.

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On-Demand Webinars

From Oncology Issues

  • Views: Fertility Preservation for Women with Cancer
    James Grifo, MD, PHD
    Advancements in reproductive science has provided more options for women to take greater control of their reproductive future.
  • Action
    ACCC and AstraZeneca were recognized for their joint effort in the Rural Appalachian Lung Cancer Screening Initiative at the Cancer Moonshot: Goals Forum hosted, by the President and First Lady.
  • Tech Solutions Ahead!
    By David R. Penberthy, MD, MBA
    Technology-drive solutions will be essential in the future of cancer care, and providing the information, education and resources health care providers need to implement those solutions is important.
  • Holy Smokes! Developing a Cannabis Clinic for Patients with Cancer
    By Sarah Jax, Katherine Schmiechen, and Dylan M. Zylla
    The HealthPartners Frauenshuh Cancer Center has safely incorporated cannabis in the treatment of patients with cancer.
  • Welcome to ACORI
    Barbara A. Gabriel
    Under ACORI, ACCC helps community oncology programs access the tools, knowledge sharing, effective practices, and peer mentorships that can increase their ability to offer clinical trials.


  1. 1Institute of Medicine (US) Forum on Drug Discovery, Development, and Translation. Transforming Clinical Research in the United States: Challenges and Opportunities: Workshop Summary. Washington (DC): National Academies Press (US); 2010.
  2. 2Stensland KD, et al. Adult Cancer Clinical Trials That Fail to Complete: An Epidemic? JNCI. September 2014;106(9).