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Optimizing Germline and Somatic Testing in Prostate Cancer –[Podcast] Ep 197

July 2, 2025

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Genetic factors play a critical role in prostate cancer treatment planning, with both germline and somatic mutations guiding therapeutic decisions. The Association of Cancer Care Centers (ACCC) remains committed to improving prostate cancer care and has developed the Metastatic Prostate Cancer Handbook: A Guide to Optimizing Outcomes with Germline and Somatic Testing. In this episode, CANCER BUZZ speaks with Andrea Murphy, FNP-C, ACGN, CGRA, genetics nurse practitioner at Mary Bird Perkins Cancer Center and Amy D. Smith, FNP-BC, director at Meredith & Jeannie Ray Cancer Center, about the impact this handbook has had on patient care delivery, measuring success during the pilot program, and recommendations for sustaining germline and somatic mutation testing in clinical practice. 

“I think a lot of people were surprised, definitely with germline testing, that all metastatic patients met the criteria [for testing]…” – Andrea (Ani) Murphy, FNP-C, ACGN, CGRA

“The other thing that the [hand]book did is [give] us a good outline on what our deficiencies were, where we wanted to go with testing...and just pretty much set it up so that it was easy for us to follow.” – Amy D. Smith, NP-BC

“Overall, I think the handbook could give anybody the guidance that they need to set up their own program.” – Amy D. Smith, NP-BC

 

 

Guests:

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Andrea (Ani) Murphy, FNP-C, ACGN, CGRA

Nurse Practitioner – Genetics  

Mary Bird Perkins Cancer Center 

Baton Rouge, LA 

 

 

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Amy D. Smith, FNP-BC

Director 

Meredith & Jeannie Ray Cancer Center 

Ivinson Memorial Hospital   

                                      Laramie, Wyoming

 

 

Resources:

ACCC Metastatic Prostate Cancer Handbook: A Guide to Optimizing Outcomes with Germline and Somatic Testing 

Understanding the Uptake and Challenges of Genetic Testing Guidelines for Prostate Cancer 

NCCN Guidelines and Frameworks for Prostate Cancer

ACCC Prostate Cancer Resources 

 

          The views and opinions expressed herein are those of the author(s)/faculty member(s) and do not reflect the official policy or position of their employer(s) or the Association of Community Cancer Centers.