Cleveland Clinic launched a monthly irAE tumor board in September 2017. The goal was to obtain specialist opinions about the side effects experienced by immunotherapy patients and to review the latest literature from the rapidly evolving field.
The original irAE tumor board consisted of a handful of oncologists and rheumatologists with specific research interest in immune-related toxicities. Since then, the irAE tumor board has grown to include specialists in gastroenterology, endocrinology, cardiology, infectious disease, urology, pulmonology, and hepatology. Additional specialists sit in on meetings if their specific expertise is required. Approximately 15 to 20 people attend each meeting.

In a recent article from Oncology Issues, authors conducted a systematic literature review and found that two main drivers of care disparities exist for transgender and nonbinary individuals with cancer: rigid binary gender frameworks and gaps in mental health care.

2026 ACCC Innovator Award Winner St. Luke's Cancer Institute noticed a significant administrative burden being placed on providers to review medical necessity validation for complex oncology therapies. To address the resulting rise in peer-to-peer requirements, delays in care, and pre-service denials, the team designed and implemented a new Clinical Documentation Integrity Registered Nurse role.

ACCC launched its Precision Medicine Stewardship Program to highlight institutions that have successfully built the infrastructure, workflows, and leadership models needed to deliver precision medicine at scale. TriHealth Cancer and Blood Institute in Cincinnati, Ohio, offers a compelling example of what it takes to move from aspiration to execution.

Although patients with relapsed or refractory multiple myeloma now have more treatment options than ever, their journeys are often complex. As clinicians consider when to introduce newer therapies such as bispecific antibodies, they must account for prior treatments, treatment-related toxicities, and comorbidities that may impact treatment decisions.
