Aptium Oncology
8201 Beverly Blvd.
Los Angeles, CA 90048
Phone: 1-877-APTIUM2

Company Information
For more than 20 years, Aptium Oncology, formerly known as Salick Health Care, has been an innovator in cancer care, working with hospitals and physicians to design, build and manage cancer centers at leading hospitals nationwide—advancing cancer treatment and patient care environments by bringing core clinical services to one central place.

Aptium Oncology’s innovative vision of cancer care has evolved into the creation of a national network of managed cancer centers at major teaching and community hospitals and more than 150 affiliated physicians. As a result of common management, these centers benefit from a real network effect in areas such as program development, equipment and medical supplies purchasing and the development of operational best practices.

The Company was founded in 1983 and is a wholly owned subsidiary of AstraZeneca, a major international healthcare company.

Cancer Center Oncology Services
Aptium Oncology promotes a comprehensive care experience for cancer patients. Each facility managed by Aptium Oncology offers individualized and personalized care for the detection, diagnosis and treatment of cancer. This care environment is established and maintained by creating a comfortable setting where a broad range of services is offered in an atmosphere of professionalism, encouragement and understanding. The staff of experts at each cancer center provides superior clinical care in tandem with important support services that play an integral role in a patient's overall care experience. Personalized specialty services include:

• Medical Oncologists
• Radiation Oncologists
• Surgical Oncologists
• Gynecologic Oncologists
• Radiation Physicists
• Psychiatrists and Psychologists
• Laboratory Technicians
• Social Work Professionals
• Pain Management Specialists
• Nutritionists
• Oncology Nurses
• Pharmacists
• Financial Counselors

Driving New Treatment Options
Aptium Oncology is committed to investing in proven technology that will keep the cancer centers' programs at the forefront of clinical care and operational performance. By standardizing many of these systems across the network, Aptium Oncology is able to achieve valuable efficiencies and cost savings, resulting in “best practices” which allow for rapid development of new programs and continuous implementation of process improvements.

Professional “Environments for Achievement”
Aptium Oncology views each cancer center as an “environment for achievement.” A place where physicians can achieve professional fulfillment and breakthroughs in patient care, and hospitals can achieve previously unattainable results for their business operations and communities. We are committed to fostering the professional achievements of each person who crosses the threshold of a cancer center. Collectively, these achievements work to bring us one step closer to our ultimate goal—longer better lives for cancer patients and their families.

Bringing The Best Together
The Aptium Oncology Research Network brings together a unified, multi-site cancer care network of collaborating physicians practicing in both cancer centers and physician practices. This consortium designs, performs and analyzes phase I through IV clinical trials focused in the field of oncology.

Aptium Oncology has a 13-year track record conducting clinical trials. Our multidisciplinary disease and modality committees serve as expert consultants to the oncology industry. We offer valuable resource to sponsors, including access to a network of seasoned clinical researchers and more than 30,000 cancer patients nationwide. In addition, our experienced research department can provide clinical trial support services, including grant development and promotion.

Looking to the future, Aptium Oncology will continue to promote and develop an innovative clinical research network as a means to improve patient care and cancer treatment.

Consulting Services
Aptium Oncology brings together an experienced management team with the skills and resources to help its clients build and operate successful cancer programs. In any environment, we are experts in working with physicians, community hospitals, and academic medical centers. Aptium Oncology offers a broad menu of consulting services including:

• Feasibility study and business plan development
• Clinical program development
• Revenue and operation analysis
• Information technology infrastructure, software and process design
• Clinical research program development
• Facility design and planning
• Physician recruitment
• Equipment procurement services
• Administrative and clinical staff recruitment and training
• Operational start-up

Moving Forward
To sustain and build on its legacy of innovation in cancer care, a key priority for the Company is growth through productive, long-term relationships with leading physicians and medical institutions. Growth will take the form of network expansion, both domestically and internationally as well as continued investment in clinical and information technology solutions that will keep the cancer centers at the forefront of clinical care and operational performance.

Comprehensive Cancer Center Locations
Aptium Oncology works with hospitals throughout the United States at nine locations, including over 100 employees at the Company’s corporate offices located in Los Angeles, and nearly 900 healthcare professionals at nine leading cancer centers:

• Alta Bates Summit Comprehensive Cancer Center – Berkeley, Calif.
• Cedars-Sinai Outpatient Cancer Center at the Samuel Oschin Comprehensive Cancer Institute – Los Angeles, Calif.
• Comprehensive Cancer Center at Desert Regional Medical Center – Palm Springs, Calif.
• NYU Clinical Cancer Center – New York, N.Y.
• St. Vincent's Comprehensive Cancer Center – New York, N.Y.
• Trinitas Comprehensive Cancer Center – Elizabeth, N.J.
• Lynn Regional Cancer Center West – Boca Raton, Fla.
• Mount Sinai Comprehensive Cancer Center – Miami, Fla.
• Mount Sinai Comprehensive Cancer Center – Aventura, Fla.

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Oncology Therapeutics Network (OTN)
395 Oyster Point Boulevard, Suite 500
South San Francisco, CA 94080
Phone: 800.482.6700

Company Information
OTN provides comprehensive services, including technology, pharmaceuticals, supportive care products, and medical and surgical supplies to physicians practicing in the community-treatment setting. The company is committed to providing its customers with the support and resources necessary to ensure their success. These include distribution resources, technology and practice management solutions, clinical services, educational opportunities, and more:

• Best-in-class pricing: OTN provides best-in-class pharmaceutical pricing, distribution services, and customer service and is committed to being the low-cost provider of drugs.
• Technology resources and practice management: Lynx® is OTN’s oncology-specific, web-based technology platform that helps physician practices increase revenue, get paid faster, and succeed with quality care initiatives.
• Clinical services: OTN’s knowledgeable clinical team is led by Kim Bergstrom, a recognized leader in development and implementation of clinical guidelines and programs within community oncology.
• OTN specialty services: OTN’s specialty pharmacy provides patients convenient home delivery of oral anti-cancer medications. Practices will be able to track patients’ compliance to their oral medication regimens through monthly tracking reports. OTN Specialty Pharmacy also has a benefits investigation team that eases the administrative burden of dealing with pre-authorizations and insurance claims.
• Sales and marketing resources: OTN has a robust sales and marketing staff dedicated to the community oncology market.

Onmark
Onmark, an OTN company, is one of the largest GPOs in the community setting, with more than 2,400 members representing 4,000+ physicians and over $6 billion in annual drug purchases.

Through strategic relationships with OTN, pharmaceutical companies, and industry experts, Onmark helps its members save money, increase efficiency, and stay informed by offering a wide variety of services, including:

• A competitive contract portfolio that offers significant savings on the majority of the most widely-used chemotherapy, biologic, and supportive care agents, both brand and generic.
• Educational programs covering clinical, practice management, and legislative topics.
• The Regimen Profiler™, a web-based tool that helps practices and patients understand financial and clinical information for many disease treatment regimens.
• The Annual Office-Based Oncology Business Benchmarking Survey, which captures key operational and financial benchmarks from community oncology practices nationwide. Respondents receive a copy of the survey results so that they may compare their own metrics to national standards and evaluate performance over time. Over 160 practices in 35 states participated in the 2007 survey.
• A clinical trial network. In January 2007, Onmark partnered with Quintiles to create a national clinical trial network of Onmark members. Through this partnership, Onmark members have the opportunity to participate in Phase II and Phase III clinical trials of investigational cancer treatments.
• Online clinical materials that are written the way chemotherapy is administered—by regimen. Treatment Information Sheets help patients understand the treatment they will receive and Clinical Outcomes Tables help staff evaluate different treatment options.
• The Clinical Reporting Initiative (CRI) Program. Onmark members using the Lynx MobileTM module can participate in the CRI Program. Participants earn money by providing recent treatment decision insights from their practice.
• he Preparation Techniques for Hazardous Drugs (PTHD) Program. This program is a convenient way for new or experienced oncology nursing staff to review the fundamentals of handling and preparing hazardous drugs including chemotherapy. The program is approved for a total of 5.0 contact hours by the Oncology Nursing Society (ONS).

To join Onmark, download an enrollment application on www.onmarkservices.com or call 866.686.8340. There are no fees or purchase requirements, and you will receive immediate access to all member benefits.

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US Oncology
16825 Northchase Drive
Suite 1300
Houston, Texas 77060
Phone: 832. 601.8766

Company Information
US Oncology is a healthcare services network dedicated exclusively to cancer treatment and research. It provides physicians with extensive services and support. US Oncology is affiliated with over 900 physicians practicing in approximately 460 locations, including 85 outpatient cancer centers in 32 states.

US Oncology's support and services can easily be categorized into two primary areas: Comprehensive Strategic Alliances and Oncology Pharmaceutical Services.

Comprehensive Strategic Alliances.
Since 1993, US Oncology has grown to become an extensive health-care services network that is devoted exclusively to cancer treatment and research. From coast to coast, US Oncology helps more than 900 independent physicians operate nearly 460 practice sites in 32 states, including 85 comprehensive cancer centers. These progressive, thought-leading physicians treat more than 350,000 patients each year. US Oncology works hard to ensure that they have unprecedented access to the latest in technological and therapeutic advantages for their patients, as well as the financial tools and management expertise they need to build their practices in their local communities.

Because of its intense focus on cancer, US Oncology can offer invaluable resources to physicians in the business of oncology. Through its many years of experience, US Oncology has developed an extensive understanding of how practices operate and can provide physicians with strategic services and support to enhance their control of their practice, from electronic medical records to managed care contracting, and from strategic data reports regarding practice performance to the ability to offer the full continuum of oncology care.

US Oncology also provides capital for growth and deliver critical support in recruiting new physicians for their practices.

Oncology Pharmaceutical Services.
US Oncology offers community-based oncology practices a range of services designed to increase practice success – especially in today’s turbulent reimbursement environment.

The oncology drug management process is complex, and minor inefficiencies can significantly impact both quality and practice performance. Our programs and services help the community-based oncology practice optimize their drug management processes. These time-tested programs and services reflect oncology pharmacy best practices and are tailored to fit the needs of each specific practice.

Providing customers with access to an on-site pharmacist is the hallmark of Oncology Pharmaceutical Services. These oncology professionals work either full-time or as a consultant, and can become a key player on your practice's team, helping to increase quality, productivity, and performance. US Oncology's Oncology Pharmaceutical Services offer today's community-based oncology practices a flexible offering of services designed to enhance practice performance. These services are structured around three core capabilities:

• Bio-Pharmaceutical Contracting Services
• Oncology Drug Management Services
• Oncology Practice Services

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